Compound Detail
CHEMBL2005548
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Basic Information
| ChEMBL ID | CHEMBL2005548 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SKLNUYVBOFIJAT-UHFFFAOYSA-N |
8
Targets
8
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
487.3
MW (Da)
5.08
ALogP
8
HBA
2
HBD
102.3
PSA (Ų)
0.38
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 8 meas. best 7.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rho-associated protein kinase 2 CHEMBL2973 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| Rho-associated protein kinase 1 CHEMBL3231 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Serine/threonine-protein kinase Chk2 CHEMBL2527 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Ribosomal protein S6 kinase alpha-3 CHEMBL2345 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha CHEMBL4101 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Serine/threonine-protein kinase PAK 1 CHEMBL4600 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Serine/threonine-protein kinase D2 CHEMBL4900 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine