Compound Detail
CHEMBL3911621
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
COc1cc(OC)cc(N(c2ccc3ncc(-c4cnn(C)c4)nc3c2)[C@H]2CC[C@@H](NC(C)C)CC2)c1
Basic Information
| ChEMBL ID | CHEMBL3911621 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AHSYHYFTUKZLCI-SZPZYZBQSA-N |
6
Targets
9
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
500.6
MW (Da)
5.49
ALogP
8
HBA
1
HBD
77.3
PSA (Ų)
0.34
QED
2
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 9 meas. best 8.75
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fibroblast growth factor receptor 2 CHEMBL4142 | IC50 | 8.75 | 8.75 | 1.8 | 1 |
| Fibroblast growth factor receptor 1 CHEMBL3650 | IC50 | 8.73 | 8.305 | 1.9 | 2 |
| Fibroblast growth factor receptor 3 CHEMBL2742 | IC50 | 8.51 | 8.19 | 3.1 | 2 |
| Fibroblast growth factor receptor 4 CHEMBL3973 | IC50 | 8.17 | 8.17 | 6.8 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | IC50 | 7.47 | 6.745 | 33.9 | 2 |
| Receptor-type tyrosine-protein kinase FLT3 CHEMBL1974 | IC50 | 5.07 | 5.07 | 8511.4 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine