Compound Detail
CHEMBL3943860
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
COc1cc(OC)cc(N(CCN2CCC[C@H]2C)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1.Cl
Basic Information
| ChEMBL ID | CHEMBL3943860 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CHNWMSQQHAFKHI-FSRHSHDFSA-N |
| Parent Compound | CHEMBL3990222 |
| Active Moiety | CHEMBL3990222 |
5
Targets
9
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
472.6
MW (Da)
4.67
ALogP
8
HBA
0
HBD
68.5
PSA (Ų)
0.37
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 9 meas. best 8.81
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fibroblast growth factor receptor 1 CHEMBL3650 | IC50 | 8.81 | 8.145 | 1.5 | 2 |
| Fibroblast growth factor receptor 2 CHEMBL4142 | IC50 | 8.7 | 8.7 | 2.0 | 1 |
| Fibroblast growth factor receptor 3 CHEMBL2742 | IC50 | 8.4 | 7.18 | 4.0 | 3 |
| Fibroblast growth factor receptor 4 CHEMBL3973 | IC50 | 8.18 | 8.18 | 6.6 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | IC50 | 7.43 | 6.89 | 37.1 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine