Compound Detail
CHEMBL1969755
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Basic Information
| ChEMBL ID | CHEMBL1969755 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JIFGOPCFXJIPNK-UHFFFAOYSA-N |
11
Targets
11
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
350.4
MW (Da)
3.22
ALogP
3
HBA
2
HBD
62.2
PSA (Ų)
0.72
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 11 meas. best 6.9
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rho-associated protein kinase 2 CHEMBL2973 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| cAMP-dependent protein kinase catalytic subunit PRKX CHEMBL5818 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha CHEMBL4101 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Ribosomal protein S6 kinase alpha-5 CHEMBL4237 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Rho-associated protein kinase 1 CHEMBL3231 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| cGMP-dependent protein kinase 1 CHEMBL4273 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Ribosomal protein S6 kinase alpha-4 CHEMBL3125 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Mitogen-activated protein kinase 1 CHEMBL4040 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| LIM domain kinase 1 CHEMBL3836 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine