Compound Detail
CHEMBL1970821
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Basic Information
| ChEMBL ID | CHEMBL1970821 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PTZQSGFNHIVQKV-UHFFFAOYSA-N |
9
Targets
9
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
316.8
MW (Da)
3.46
ALogP
4
HBA
3
HBD
73.8
PSA (Ų)
0.48
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 9 meas. best 9.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cell division cycle 7-related protein kinase CHEMBL5443 | Ki | 9.1 | 9.1 | 0.8 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 8.5 | 8.5 | 3.2 | 1 |
| Rho-associated protein kinase 2 CHEMBL2973 | Ki | 7.8 | 7.8 | 15.8 | 1 |
| Homeodomain-interacting protein kinase 2 CHEMBL4576 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 7.0 | 7.0 | 100.0 | 1 |
| Cyclin-dependent kinase 2 CHEMBL301 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha CHEMBL4101 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Interleukin-1 receptor-associated kinase 4 CHEMBL3778 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine