Compound Detail
CHEMBL1972250
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Basic Information
| ChEMBL ID | CHEMBL1972250 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WOTLXQZLXOXMFD-UHFFFAOYSA-N |
10
Targets
10
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
312.3
MW (Da)
2.90
ALogP
4
HBA
1
HBD
74.6
PSA (Ų)
0.58
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 10 meas. best 7.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serine/threonine-protein kinase Chk1 CHEMBL4630 | Ki | 7.4 | 7.4 | 39.8 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 CHEMBL1974 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Ribosomal protein S6 kinase alpha-3 CHEMBL2345 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Tyrosine-protein kinase JAK2 CHEMBL2971 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Serine/threonine-protein kinase Chk2 CHEMBL2527 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Aurora kinase A CHEMBL4722 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Macrophage colony-stimulating factor 1 receptor CHEMBL1844 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Ribosomal protein S6 kinase beta-1 CHEMBL4501 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| MAP/microtubule affinity-regulating kinase 3 CHEMBL5600 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine