Compound Detail
CHEMBL3908326
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
COc1cc(OC)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(CC5(OC)CCNCC5)c4)nc3c2)c1
Basic Information
| ChEMBL ID | CHEMBL3908326 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IJNFMKJSNQLEOT-UHFFFAOYSA-N |
6
Targets
11
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
528.7
MW (Da)
4.83
ALogP
9
HBA
1
HBD
86.6
PSA (Ų)
0.31
QED
1
Ro5 Violations
10
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 11 meas. best 8.75
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fibroblast growth factor receptor 3 CHEMBL2742 | IC50 | 8.75 | 6.5733 | 1.8 | 3 |
| Fibroblast growth factor receptor 1 CHEMBL3650 | IC50 | 8.7 | 7.39 | 2.0 | 2 |
| Fibroblast growth factor receptor 2 CHEMBL4142 | IC50 | 8.26 | 8.26 | 5.5 | 1 |
| Fibroblast growth factor receptor 4 CHEMBL3973 | IC50 | 7.17 | 7.17 | 67.6 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | IC50 | 7.01 | 5.8033 | 97.7 | 3 |
| Receptor-type tyrosine-protein kinase FLT3 CHEMBL1974 | IC50 | 5.26 | 5.26 | 5495.4 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine