Compound Detail
CHEMBL3970423
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
COc1cc(OC)cc(N(CCC2CCN(C(C)C)CC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1
Basic Information
| ChEMBL ID | CHEMBL3970423 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IWWFPZKWURVISH-UHFFFAOYSA-N |
6
Targets
13
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
514.7
MW (Da)
5.70
ALogP
8
HBA
0
HBD
68.5
PSA (Ų)
0.28
QED
2
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 13 meas. best 8.9
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fibroblast growth factor receptor 1 CHEMBL3650 | IC50 | 8.9 | 6.9467 | 1.3 | 3 |
| Fibroblast growth factor receptor 3 CHEMBL2742 | IC50 | 8.68 | 6.94 | 2.1 | 3 |
| Fibroblast growth factor receptor 2 CHEMBL4142 | IC50 | 8.64 | 8.64 | 2.3 | 1 |
| Fibroblast growth factor receptor 4 CHEMBL3973 | IC50 | 8.0 | 8.0 | 10.0 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | IC50 | 7.57 | 6.1867 | 26.9 | 3 |
| Receptor-type tyrosine-protein kinase FLT3 CHEMBL1974 | IC50 | 5.3 | 5.275 | 5011.9 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine