Compound Detail
CHEMBL1302524
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Basic Information
| ChEMBL ID | CHEMBL1302524 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SLPYZNNPGREBMV-UHFFFAOYSA-N |
11
Targets
16
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
369.8
MW (Da)
3.27
ALogP
4
HBA
1
HBD
91.8
PSA (Ų)
0.90
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 16 meas. best 6.65
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Voltage-gated N-type calcium channel alpha-1B subunit/Amyloid beta A4 precursor protein-binding family A member 1 CHEMBL2097170 | IC50 | 6.65 | 6.06 | 225.0 | 2 |
| Unchecked CHEMBL612545 | IC50 | 5.56 | 5.41 | 2744.0 | 3 |
| Apoptotic protease-activating factor 1 CHEMBL1795093 | IC50 | 5.54 | 5.54 | 2920.0 | 1 |
| SUMO-activating enzyme CHEMBL2095174 | IC50 | 5.42 | 5.09 | 3770.0 | 2 |
| Sentrin-specific protease 6 CHEMBL1741215 | IC50 | 5.39 | 5.39 | 4080.0 | 1 |
| Sentrin-specific protease 8 CHEMBL1741207 | IC50 | 5.22 | 5.22 | 5990.0 | 1 |
| Hexokinase HKDC1 CHEMBL1741200 | IC50 | 5.21 | 5.135 | 6230.0 | 2 |
| DNA dC->dU-editing enzyme APOBEC-3G CHEMBL1741217 | IC50 | 5.09 | 5.09 | 8030.0 | 1 |
| Sentrin-specific protease 7 CHEMBL1741213 | IC50 | 5.05 | 5.05 | 8900.0 | 1 |
| Tyrosyl-DNA phosphodiesterase 2 CHEMBL2169736 | IC50 | 5.03 | 5.03 | 9395.0 | 1 |
| Caspase-3 CHEMBL2334 | IC50 | 4.85 | 4.85 | 14200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine