Compound Detail
CHEMBL1375418
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1375418 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PWNFEFRGKMPFSG-UHFFFAOYSA-N |
11
Targets
11
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
315.4
MW (Da)
3.71
ALogP
5
HBA
1
HBD
55.1
PSA (Ų)
0.62
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 11 meas. best 6.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Serine/threonine-protein kinase pim-3 CHEMBL5407 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 CHEMBL4045 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 5 CHEMBL4852 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| MAP/microtubule affinity-regulating kinase 3 CHEMBL5600 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| SRSF protein kinase 1 CHEMBL4375 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Lymphokine-activated killer T-cell-originated protein kinase CHEMBL4896 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Serine/threonine-protein kinase TAO1 CHEMBL5261 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| Serine/threonine-protein kinase D3 CHEMBL2595 | Ki | 5.0 | 5.0 | 10000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine