Compound Detail
CHEMBL1999496
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Basic Information
| ChEMBL ID | CHEMBL1999496 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MJLKHAZEWYICMC-UHFFFAOYSA-N |
9
Targets
9
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
342.4
MW (Da)
4.64
ALogP
2
HBA
1
HBD
42.0
PSA (Ų)
0.75
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 9 meas. best 6.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serine/threonine-protein kinase PLK3 CHEMBL4897 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Epidermal growth factor receptor CHEMBL203 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Tyrosine-protein kinase FRK CHEMBL4223 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Protein kinase C delta type CHEMBL2996 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha CHEMBL4101 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| STE20-like serine/threonine-protein kinase CHEMBL4202 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Serine/threonine-protein kinase Nek4 CHEMBL5819 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine