Compound Detail
CHEMBL1392911
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Basic Information
| ChEMBL ID | CHEMBL1392911 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FXZNHTKAOTUVHO-UHFFFAOYSA-N |
8
Targets
12
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
316.4
MW (Da)
3.73
ALogP
5
HBA
2
HBD
59.4
PSA (Ų)
0.44
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 11 meas. best 5.64
EC50 1 meas. best 4.76
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sentrin-specific protease 6 CHEMBL1741215 | IC50 | 5.64 | 5.64 | 2300.0 | 1 |
| Sentrin-specific protease 8 CHEMBL1741207 | IC50 | 5.56 | 5.56 | 2740.0 | 1 |
| Sentrin-specific protease 7 CHEMBL1741213 | IC50 | 5.39 | 5.39 | 4080.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 5.18 | 4.966 | 6620.0 | 5 |
| Caspase-3 CHEMBL2334 | IC50 | 5.12 | 5.12 | 7540.0 | 1 |
| Tyrosyl-DNA phosphodiesterase 2 CHEMBL2169736 | IC50 | 5.0 | 5.0 | 9935.0 | 1 |
| Apoptotic protease-activating factor 1 CHEMBL1795093 | IC50 | 4.97 | 4.97 | 10800.0 | 1 |
| Protein RecA CHEMBL1741171 | EC50 | 4.76 | 4.76 | 17500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine