Compound Detail
CHEMBL1421377
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Basic Information
| ChEMBL ID | CHEMBL1421377 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QRFUTURFHZKKPS-UHFFFAOYSA-N |
9
Targets
11
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
334.8
MW (Da)
6.05
ALogP
3
HBA
0
HBD
15.6
PSA (Ų)
0.54
QED
1
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 8 meas. best 5.72
EC50 3 meas. best 5.38
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sentrin-specific protease 6 CHEMBL1741215 | IC50 | 5.72 | 5.72 | 1890.0 | 1 |
| Sentrin-specific protease 8 CHEMBL1741207 | IC50 | 5.69 | 5.69 | 2040.0 | 1 |
| Streptococcus sp. 'group A' CHEMBL612389 | EC50 | 5.38 | 5.38 | 4169.0 | 1 |
| Sentrin-specific protease 7 CHEMBL1741213 | IC50 | 5.25 | 5.25 | 5650.0 | 1 |
| Streptokinase A CHEMBL1293228 | EC50 | 5.13 | 5.13 | 7430.0 | 1 |
| Caspase-3 CHEMBL2334 | IC50 | 5.1 | 5.1 | 7930.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 5.08 | 4.8767 | 8290.0 | 3 |
| Streptococcus CHEMBL612313 | EC50 | 4.77 | 4.77 | 17119.0 | 1 |
| Apoptotic protease-activating factor 1 CHEMBL1795093 | IC50 | 4.75 | 4.75 | 17900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine