Compound Detail
CHEMBL1973868
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Basic Information
| ChEMBL ID | CHEMBL1973868 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GKODJBVKKLQMEY-UHFFFAOYSA-N |
12
Targets
12
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
222.2
MW (Da)
3.00
ALogP
3
HBA
1
HBD
46.0
PSA (Ų)
0.69
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 12 meas. best 7.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 7.6 | 7.6 | 25.1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B CHEMBL5543 | Ki | 7.3 | 7.3 | 50.1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| Rho-associated protein kinase 1 CHEMBL3231 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Cyclin-dependent kinase 8 CHEMBL5719 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Cyclin-dependent kinase 5 CHEMBL4036 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Activin receptor type-1 CHEMBL5903 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Leucine-rich repeat serine/threonine-protein kinase 2 CHEMBL1075104 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Cyclin-dependent kinase 9 CHEMBL3116 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Dual specificity protein kinase CLK2 CHEMBL4225 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Cyclin-dependent kinase 7 CHEMBL3055 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine