Compound Detail
CHEMBL1979718
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Basic Information
| ChEMBL ID | CHEMBL1979718 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JLRRNFYWQUCREK-UHFFFAOYSA-N |
11
Targets
11
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
345.4
MW (Da)
3.68
ALogP
4
HBA
2
HBD
75.6
PSA (Ų)
0.59
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 11 meas. best 6.9
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rho-associated protein kinase 2 CHEMBL2973 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| Ribosomal protein S6 kinase beta-1 CHEMBL4501 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha CHEMBL4101 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Serine/threonine-protein kinase MRCK alpha CHEMBL4516 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Rho-associated protein kinase 1 CHEMBL3231 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| RAC-alpha serine/threonine-protein kinase CHEMBL4282 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Serine/threonine-protein kinase PLK4 CHEMBL3788 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Aurora kinase A CHEMBL4722 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| RAC-gamma serine/threonine-protein kinase CHEMBL4816 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine