Compound Detail
CHEMBL1980704
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Basic Information
| ChEMBL ID | CHEMBL1980704 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QGOIQRQXIWSNJF-UHFFFAOYSA-N |
11
Targets
11
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
345.4
MW (Da)
4.13
ALogP
6
HBA
0
HBD
47.5
PSA (Ų)
0.46
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 11 meas. best 7.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serine/threonine-protein kinase pim-3 CHEMBL5407 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| Serine/threonine-protein kinase pim-2 CHEMBL4523 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Death-associated protein kinase 3 CHEMBL2468 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Ribosomal protein S6 kinase beta-1 CHEMBL4501 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Casein kinase II subunit alpha CHEMBL3629 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Ribosomal protein S6 kinase alpha-3 CHEMBL2345 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Rho-associated protein kinase 2 CHEMBL2973 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine