Compound Detail
CHEMBL2432039
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Basic Information
| ChEMBL ID | CHEMBL2432039 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CHZUEGVOEFMIJH-ZKRSMWHSSA-N |
16
Targets
16
Activities
1
Assay Types
0
PK Parameters
20
Publications
0
Known Names
Molecular Properties
277.4
MW (Da)
2.09
ALogP
1
HBA
1
HBD
12.0
PSA (Ų)
0.83
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 16 meas. best 8.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | Ki | 8.7 | 8.7 | 2.0 | 1 |
| Sigma non-opioid intracellular receptor 1 CHEMBL3602 | Ki | 8.52 | 8.52 | 3.0 | 1 |
| Sodium-dependent dopamine transporter CHEMBL238 | Ki | 6.9 | 6.9 | 126.0 | 1 |
| Muscarinic acetylcholine receptor M2 CHEMBL211 | Ki | 6.71 | 6.71 | 195.0 | 1 |
| Muscarinic acetylcholine receptor M4 CHEMBL1821 | Ki | 6.45 | 6.45 | 354.0 | 1 |
| Muscarinic acetylcholine receptor M3 CHEMBL245 | Ki | 6.33 | 6.33 | 466.0 | 1 |
| Muscarinic acetylcholine receptor M5 CHEMBL2035 | Ki | 6.22 | 6.22 | 595.0 | 1 |
| Alpha-2C adrenergic receptor CHEMBL1916 | Ki | 6.17 | 6.17 | 683.0 | 1 |
| Kappa-type opioid receptor CHEMBL237 | Ki | 6.09 | 6.09 | 809.0 | 1 |
| Alpha-2B adrenergic receptor CHEMBL1942 | Ki | 6.0 | 6.0 | 1005.0 | 1 |
| Histamine H1 receptor CHEMBL231 | Ki | 5.33 | 5.33 | 4736.0 | 1 |
| D(3) dopamine receptor CHEMBL234 | Ki | 5.27 | 5.27 | 5365.0 | 1 |
| D(2) dopamine receptor CHEMBL217 | Ki | 5.25 | 5.25 | 5675.0 | 1 |
| Histamine H2 receptor CHEMBL1941 | Ki | 5.2 | 5.2 | 6268.0 | 1 |
| Muscarinic acetylcholine receptor M1 CHEMBL216 | Ki | 5.13 | 5.13 | 7468.0 | 1 |
| 5-hydroxytryptamine receptor 5A CHEMBL3426 | Ki | 5.12 | 5.12 | 7502.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
Data from ChEMBL 36 via Core Engine