Compound Detail
CHEMBL448741
DIHYDROSPINGOSINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL448741 |
| Name | DIHYDROSPINGOSINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OTKJDMGTUTTYMP-ZWKOTPCHSA-N |
9
Targets
18
Activities
2
Assay Types
0
PK Parameters
20
Publications
0
Known Names
Molecular Properties
301.5
MW (Da)
4.15
ALogP
3
HBA
3
HBD
66.5
PSA (Ų)
0.38
QED
0
Ro5 Violations
16
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 11 meas. best 5.46
EC50 7 meas. best 5.87
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Streptococcus sp. 'group A' CHEMBL612389 | EC50 | 5.87 | 5.87 | 1338.0 | 1 |
| Streptokinase A CHEMBL1293228 | EC50 | 5.66 | 5.66 | 2204.0 | 1 |
| FL5.12 CHEMBL4296414 | IC50 | 5.46 | 5.46 | 3500.0 | 1 |
| Jurkat CHEMBL397 | IC50 | 5.45 | 5.3475 | 3530.0 | 4 |
| Unchecked CHEMBL612545 | EC50 | 5.12 | 5.0075 | 7582.0 | 4 |
| Streptococcus CHEMBL612313 | EC50 | 5.05 | 5.05 | 8911.0 | 1 |
| Plasmodium falciparum CHEMBL364 | IC50 | 5.0 | 4.9333 | 10000.0 | 3 |
| Cholesteryl ester transfer protein CHEMBL3572 | IC50 | 4.89 | 4.89 | 12900.0 | 1 |
| Ubiquitin-conjugating enzyme E2 N CHEMBL6089 | IC50 | 4.87 | 4.84 | 13378.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
Data from ChEMBL 36 via Core Engine