Compound Detail
CHEMBL1318350
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Basic Information
| ChEMBL ID | CHEMBL1318350 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WXTVEUVKCYUVQQ-UHFFFAOYSA-M |
| Parent Compound | CHEMBL1617424 |
| Active Moiety | CHEMBL1617424 |
10
Targets
19
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
403.6
MW (Da)
6.60
ALogP
3
HBA
0
HBD
7.1
PSA (Ų)
0.36
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 16 meas. best 7.34
IC50 3 meas. best 5.51
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 7.34 | 5.95 | 46.0 | 3 |
| Beta-adrenergic receptor kinase 1 CHEMBL4079 | EC50 | 6.92 | 6.92 | 120.0 | 1 |
| BJ CHEMBL614358 | EC50 | 6.43 | 6.07 | 370.0 | 4 |
| ATP-dependent molecular chaperone HSP82 CHEMBL1293251 | EC50 | 5.76 | 5.13 | 1745.0 | 2 |
| Streptokinase A CHEMBL1293228 | EC50 | 5.63 | 5.63 | 2339.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 5.51 | 4.9133 | 3100.0 | 3 |
| Streptococcus sp. 'group A' CHEMBL612389 | EC50 | 5.48 | 5.48 | 3288.0 | 1 |
| Streptococcus CHEMBL612313 | EC50 | 5.35 | 5.35 | 4438.0 | 1 |
| Alkaline phosphatase, tissue-nonspecific isozyme CHEMBL5979 | EC50 | 4.22 | 4.22 | 60600.0 | 1 |
| Intestinal-type alkaline phosphatase CHEMBL5573 | EC50 | 4.21 | 4.21 | 61800.0 | 1 |
| Alkaline phosphatase, germ cell type CHEMBL3402 | EC50 | 4.18 | 4.18 | 65300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine