Compound Detail
CHEMBL1975256
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Basic Information
| ChEMBL ID | CHEMBL1975256 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DZCWNAMURCVSNJ-UHFFFAOYSA-N |
14
Targets
14
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
386.4
MW (Da)
1.79
ALogP
11
HBA
2
HBD
137.1
PSA (Ų)
0.39
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 14 meas. best 7.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 7.3 | 7.3 | 50.1 | 1 |
| Serine/threonine-protein kinase MRCK alpha CHEMBL4516 | Ki | 7.2 | 7.2 | 63.1 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Cyclin-dependent kinase 2 CHEMBL301 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Aurora kinase A CHEMBL4722 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Rho-associated protein kinase 2 CHEMBL2973 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Rho-associated protein kinase 1 CHEMBL3231 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Cyclin-dependent kinase 1 CHEMBL308 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Protein kinase C delta type CHEMBL2996 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Serine/threonine-protein kinase TAO1 CHEMBL5261 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Serine/threonine-protein kinase N2 CHEMBL3032 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Cyclin-dependent kinase 5 CHEMBL4036 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine