Compound Detail
CHEMBL2003768
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Basic Information
| ChEMBL ID | CHEMBL2003768 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QUZYEJUYJAWLOF-UHFFFAOYSA-N |
11
Targets
11
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
339.4
MW (Da)
2.05
ALogP
7
HBA
2
HBD
89.5
PSA (Ų)
0.64
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 11 meas. best 6.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Receptor tyrosine-protein kinase erbB-2 CHEMBL1824 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Serine/threonine-protein kinase MRCK alpha CHEMBL4516 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Interleukin-1 receptor-associated kinase 1 CHEMBL3357 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Ribosomal protein S6 kinase beta-1 CHEMBL4501 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Casein kinase I isoform gamma-3 CHEMBL5084 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Ribosomal protein S6 kinase alpha-3 CHEMBL2345 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha CHEMBL4101 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Rho-associated protein kinase 1 CHEMBL3231 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine