Compound Detail
CHEMBL278663
PARA-METHOXYAMPHETAMINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL278663 |
| Name | PARA-METHOXYAMPHETAMINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NEGYEDYHPHMHGK-UHFFFAOYSA-N |
7
Targets
12
Activities
4
Assay Types
0
PK Parameters
20
Publications
0
Known Names
Molecular Properties
165.2
MW (Da)
1.58
ALogP
2
HBA
1
HBD
35.2
PSA (Ų)
0.74
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 4.49
IC50 3 meas. best 6.76
Kd 3 meas. best 5.16
Ki 3 meas. best 6.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sodium-dependent serotonin transporter CHEMBL313 | IC50 | 6.76 | 6.76 | 173.0 | 1 |
| Amine oxidase [flavin-containing] A CHEMBL3358 | Ki | 6.6 | 6.6 | 250.0 | 1 |
| Amine oxidase [flavin-containing] A CHEMBL3358 | IC50 | 6.52 | 6.52 | 300.0 | 1 |
| 5-hydroxytryptamine receptor 2B CHEMBL323 | Kd | 5.16 | 5.16 | 6918.3 | 1 |
| Serotonin (5-HT) receptor CHEMBL2094123 | Kd | 5.15 | 5.15 | 7079.5 | 2 |
| Sodium-dependent serotonin transporter CHEMBL228 | EC50 | 4.49 | 4.49 | 32359.4 | 1 |
| Serotonin 2 (5-HT2) receptor CHEMBL2093870 | Ki | 4.47 | 4.47 | 33600.0 | 1 |
| Serotonin 1 (5-HT1) receptor CHEMBL2095159 | Ki | 4.1 | 4.1 | 79400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
Data from ChEMBL 36 via Core Engine