Compound Detail
CHEMBL1496705
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Basic Information
| ChEMBL ID | CHEMBL1496705 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZRENFQNCGQQLHI-UHFFFAOYSA-M |
| Parent Compound | CHEMBL1622570 |
| Active Moiety | CHEMBL1622570 |
8
Targets
16
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
451.6
MW (Da)
6.04
ALogP
4
HBA
0
HBD
44.3
PSA (Ų)
0.17
QED
1
Ro5 Violations
14
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 9 meas. best 5.14
EC50 7 meas. best 5.63
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 5.63 | 5.55 | 2360.0 | 2 |
| Streptokinase A CHEMBL1293228 | EC50 | 5.25 | 5.25 | 5673.0 | 1 |
| Streptococcus sp. 'group A' CHEMBL612389 | EC50 | 5.21 | 5.21 | 6202.0 | 1 |
| HEK293 CHEMBL614818 | IC50 | 5.14 | 5.14 | 7281.0 | 1 |
| Streptococcus CHEMBL612313 | EC50 | 5.1 | 5.1 | 7921.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 4.98 | 4.7429 | 10510.0 | 7 |
| Apoptotic protease-activating factor 1 CHEMBL1795093 | IC50 | 4.97 | 4.97 | 10800.0 | 1 |
| Protein RecA CHEMBL1741171 | EC50 | 4.93 | 4.93 | 11700.0 | 1 |
| Insulin-degrading enzyme CHEMBL1293287 | EC50 | 4.77 | 4.77 | 16931.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine