Compound Detail
CHEMBL1992231
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Basic Information
| ChEMBL ID | CHEMBL1992231 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IABDKYMGRMDGMM-UHFFFAOYSA-N |
14
Targets
14
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
325.3
MW (Da)
3.20
ALogP
6
HBA
3
HBD
100.0
PSA (Ų)
0.66
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 14 meas. best 8.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cell division cycle 7-related protein kinase CHEMBL5443 | Ki | 8.6 | 8.6 | 2.5 | 1 |
| Maternal embryonic leucine zipper kinase CHEMBL4578 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 7.0 | 7.0 | 100.0 | 1 |
| Serine/threonine-protein kinase 17A CHEMBL4525 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 CHEMBL1974 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Homeodomain-interacting protein kinase 2 CHEMBL4576 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Death-associated protein kinase 3 CHEMBL2468 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Cyclin-dependent kinase 9 CHEMBL3116 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Cyclin-dependent kinase 2 CHEMBL301 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Misshapen-like kinase 1 CHEMBL5518 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Cyclin-dependent kinase 5 CHEMBL4036 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Serine/threonine-protein kinase PAK 4 CHEMBL4482 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine