Compound Detail
CHEMBL1464805
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Basic Information
| ChEMBL ID | CHEMBL1464805 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UGICRKWJFNHPOX-UHFFFAOYSA-N |
11
Targets
14
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
379.8
MW (Da)
3.71
ALogP
6
HBA
1
HBD
81.4
PSA (Ų)
0.58
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 14 meas. best 5.54
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Photoreceptor-specific nuclear receptor CHEMBL4374 | IC50 | 5.54 | 5.54 | 2861.0 | 1 |
| Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 CHEMBL2096976 | IC50 | 5.3 | 5.3 | 5059.0 | 1 |
| Likely tRNA 2'-phosphotransferase CHEMBL1293308 | IC50 | 5.23 | 5.23 | 5930.0 | 1 |
| Serine/threonine-protein phosphatase PP1-alpha catalytic subunit CHEMBL2164 | IC50 | 5.18 | 5.18 | 6557.0 | 1 |
| Guanyl-specific ribonuclease T1 CHEMBL1075043 | IC50 | 5.14 | 5.14 | 7177.0 | 1 |
| 72 kDa type IV collagenase CHEMBL333 | IC50 | 5.08 | 5.08 | 8370.0 | 1 |
| Major prion protein CHEMBL4869 | IC50 | 5.04 | 5.04 | 9031.0 | 1 |
| 26S proteasome non-ATPase regulatory subunit 14 CHEMBL2007629 | IC50 | 4.92 | 4.92 | 12000.0 | 1 |
| Tyrosine-protein phosphatase non-receptor type 22 CHEMBL2889 | IC50 | 4.8 | 4.5033 | 15958.0 | 3 |
| Prothrombin CHEMBL4471 | IC50 | 4.52 | 4.52 | 30200.0 | 1 |
| Tyrosine-protein phosphatase non-receptor type 7 CHEMBL2219 | IC50 | 4.42 | 4.365 | 37880.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine