Compound Detail
CHEMBL1993374
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Basic Information
| ChEMBL ID | CHEMBL1993374 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OFGKHGRQQKNHAV-UHFFFAOYSA-N |
13
Targets
13
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
297.8
MW (Da)
3.79
ALogP
6
HBA
2
HBD
62.7
PSA (Ų)
0.88
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 13 meas. best 6.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase 8 CHEMBL2276 | Ki | 6.8 | 6.8 | 158.5 | 1 |
| Mitogen-activated protein kinase 9 CHEMBL4179 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Cyclin-dependent kinase 5 CHEMBL4036 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Macrophage colony-stimulating factor 1 receptor CHEMBL1844 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Cyclin-dependent kinase 7 CHEMBL3055 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Cyclin-dependent kinase 9 CHEMBL3116 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Calcium/calmodulin-dependent protein kinase type 1D CHEMBL5073 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B CHEMBL5543 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Leukocyte tyrosine kinase receptor CHEMBL5627 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Ribosomal protein S6 kinase alpha-3 CHEMBL2345 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Focal adhesion kinase 1 CHEMBL2695 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| ALK tyrosine kinase receptor CHEMBL4247 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine