Compound Detail
CHEMBL523200
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL523200 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FHSFUCNKKOYZKD-UHFFFAOYSA-N |
7
Targets
19
Activities
2
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
317.3
MW (Da)
3.80
ALogP
7
HBA
0
HBD
112.3
PSA (Ų)
0.53
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 13 meas. best 5.89
IC50 6 meas. best 5.43
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 5.89 | 5.5238 | 1273.0 | 8 |
| Protein RecA CHEMBL1741171 | EC50 | 5.82 | 5.82 | 1500.0 | 1 |
| BJ CHEMBL614358 | EC50 | 5.49 | 5.28 | 3270.0 | 3 |
| Unchecked CHEMBL612545 | IC50 | 5.43 | 5.43 | 3693.0 | 1 |
| X-box-binding protein 1 CHEMBL1741176 | IC50 | 5.0 | 5.0 | 10000.0 | 1 |
| DNA damage-inducible transcript 3 protein CHEMBL2146304 | IC50 | 5.0 | 5.0 | 10000.0 | 1 |
| Heat shock factor protein 1 CHEMBL5313 | EC50 | 4.93 | 4.93 | 11670.0 | 1 |
| Hexokinase HKDC1 CHEMBL1741200 | IC50 | 4.43 | 4.43 | 37400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19282190 | 10.1016/j.bmc.2009.02.046 | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine