Compound Detail
CHEMBL1492305
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Basic Information
| ChEMBL ID | CHEMBL1492305 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WVXZZGALNSGPLY-GDNBJRDFSA-N |
9
Targets
20
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
430.5
MW (Da)
4.62
ALogP
7
HBA
1
HBD
83.6
PSA (Ų)
0.45
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 18 meas. best 6.22
EC50 2 meas. best 5.47
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tyrosine-protein phosphatase non-receptor type 7 CHEMBL2219 | IC50 | 6.22 | 5.2567 | 608.0 | 3 |
| Tyrosine-protein phosphatase non-receptor type 12 CHEMBL3236 | IC50 | 5.79 | 5.79 | 1630.0 | 1 |
| Tyrosine-protein phosphatase non-receptor type 22 CHEMBL2889 | IC50 | 5.51 | 5.245 | 3100.0 | 10 |
| RNA-binding protein pos-1 CHEMBL1293304 | EC50 | 5.47 | 5.47 | 3393.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 5.35 | 5.35 | 4430.0 | 1 |
| 26S proteasome non-ATPase regulatory subunit 14 CHEMBL2007629 | IC50 | 5.28 | 5.28 | 5260.0 | 1 |
| Envelope glycoprotein gp160 CHEMBL1293311 | IC50 | 4.93 | 4.93 | 11700.0 | 1 |
| Zinc finger protein mex-5 CHEMBL1293319 | EC50 | 4.69 | 4.69 | 20376.0 | 1 |
| Prothrombin CHEMBL4471 | IC50 | 4.46 | 4.46 | 34500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine