Compound Detail
CHEMBL1966035
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Basic Information
| ChEMBL ID | CHEMBL1966035 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MCBPNFWHHNJTGN-UHFFFAOYSA-N |
17
Targets
17
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
293.3
MW (Da)
2.59
ALogP
5
HBA
2
HBD
71.1
PSA (Ų)
0.71
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 17 meas. best 6.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| cAMP-dependent protein kinase catalytic subunit PRKX CHEMBL5818 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Serine/threonine-protein kinase Chk2 CHEMBL2527 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Rho-associated protein kinase 2 CHEMBL2973 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Serine/threonine-protein kinase DCLK1 CHEMBL5683 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Serine/threonine-protein kinase 17A CHEMBL4525 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Serine/threonine-protein kinase Nek4 CHEMBL5819 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Serine/threonine-protein kinase MRCK alpha CHEMBL4516 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Rho-associated protein kinase 1 CHEMBL3231 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Casein kinase I isoform gamma-3 CHEMBL5084 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Casein kinase I isoform gamma-2 CHEMBL2543 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Interleukin-1 receptor-associated kinase 1 CHEMBL3357 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Serine/threonine-protein kinase BRSK1 CHEMBL5650 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Serine/threonine-protein kinase PLK1 CHEMBL3024 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine