Compound Detail
CHEMBL1976732
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Basic Information
| ChEMBL ID | CHEMBL1976732 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QKFXSCNWJZKJSJ-UHFFFAOYSA-N |
12
Targets
12
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
410.4
MW (Da)
3.29
ALogP
8
HBA
1
HBD
93.8
PSA (Ų)
0.49
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 12 meas. best 6.9
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Misshapen-like kinase 1 CHEMBL5518 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| MAP/microtubule affinity-regulating kinase 3 CHEMBL5600 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| Serine/threonine-protein kinase D3 CHEMBL2595 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Receptor tyrosine-protein kinase erbB-2 CHEMBL1824 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Epidermal growth factor receptor CHEMBL203 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Mitogen-activated protein kinase 9 CHEMBL4179 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Serine/threonine-protein kinase D2 CHEMBL4900 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Casein kinase I isoform delta CHEMBL2828 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Serine/threonine-protein kinase TAO1 CHEMBL5261 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine