Compound Detail
CHEMBL1992644
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Basic Information
| ChEMBL ID | CHEMBL1992644 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VOXXNSOMSGHJJR-UHFFFAOYSA-N |
18
Targets
18
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
221.3
MW (Da)
3.14
ALogP
2
HBA
1
HBD
41.6
PSA (Ų)
0.72
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 18 meas. best 6.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha CHEMBL4101 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Receptor tyrosine-protein kinase erbB-4 CHEMBL3009 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Serine/threonine-protein kinase MRCK alpha CHEMBL4516 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Tyrosine-protein kinase Lyn CHEMBL3905 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Protein kinase C delta type CHEMBL2996 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Ribosomal protein S6 kinase beta-1 CHEMBL4501 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Ribosomal protein S6 kinase alpha-3 CHEMBL2345 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Serine/threonine-protein kinase MARK2 CHEMBL3831 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Aurora kinase A CHEMBL4722 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| RAC-alpha serine/threonine-protein kinase CHEMBL4282 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| MAP/microtubule affinity-regulating kinase 3 CHEMBL5600 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| Fibroblast growth factor receptor 1 CHEMBL3650 | Ki | 5.0 | 5.0 | 10000.0 | 1 |
| Cyclin-dependent kinase 1 CHEMBL308 | Ki | 5.0 | 5.0 | 10000.0 | 1 |
| RAC-gamma serine/threonine-protein kinase CHEMBL4816 | Ki | 5.0 | 5.0 | 10000.0 | 1 |
| Protein kinase C zeta type CHEMBL3438 | Ki | 4.9 | 4.9 | 12589.2 | 1 |
| Cyclin-dependent kinase 2 CHEMBL301 | Ki | 4.9 | 4.9 | 12589.2 | 1 |
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | Ki | 4.7 | 4.7 | 19952.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine