Compound Detail
CHEMBL1548086
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Basic Information
| ChEMBL ID | CHEMBL1548086 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XNZDUZXLPJISGW-JVKBBZCWSA-M |
| Parent Compound | CHEMBL1624390 |
| Active Moiety | CHEMBL1624390 |
9
Targets
18
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
471.2
MW (Da)
9.23
ALogP
1
HBA
0
HBD
0.0
PSA (Ų)
0.18
QED
1
Ro5 Violations
13
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 12 meas. best 5.32
EC50 6 meas. best 5.84
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Streptococcus sp. 'group A' CHEMBL612389 | EC50 | 5.84 | 5.84 | 1459.0 | 1 |
| Streptokinase A CHEMBL1293228 | EC50 | 5.62 | 5.35 | 2398.0 | 2 |
| Unchecked CHEMBL612545 | EC50 | 5.59 | 5.59 | 2580.0 | 1 |
| Ubiquitin-conjugating enzyme E2 N CHEMBL6089 | IC50 | 5.32 | 5.32 | 4770.0 | 2 |
| Unchecked CHEMBL612545 | IC50 | 5.15 | 4.6757 | 7040.0 | 7 |
| Streptococcus CHEMBL612313 | EC50 | 5.14 | 5.14 | 7234.0 | 1 |
| Bcl-2-related protein A1 CHEMBL1293239 | IC50 | 5.08 | 5.08 | 8260.0 | 1 |
| Protein RecA CHEMBL1741171 | EC50 | 5.0 | 5.0 | 10100.0 | 1 |
| Apoptotic protease-activating factor 1 CHEMBL1795093 | IC50 | 4.94 | 4.94 | 11600.0 | 1 |
| Melanocortin receptor 4 CHEMBL259 | IC50 | 4.61 | 4.61 | 24314.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine