Compound Detail
CHEMBL309339
SALICYLHYDROXAMIC ACID Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL309339 |
| Name | SALICYLHYDROXAMIC ACID |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HBROZNQEVUILML-UHFFFAOYSA-N |
6
Targets
20
Activities
3
Assay Types
1
PK Parameters
20
Publications
0
Known Names
Molecular Properties
153.1
MW (Da)
0.51
ALogP
3
HBA
3
HBD
69.6
PSA (Ų)
0.41
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 12 meas. best 5.52
EC50 7 meas. best 5.16
Kd 1 meas. best 5.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Myeloperoxidase CHEMBL2439 | Kd | 5.7 | 5.7 | 2000.0 | 1 |
| Myeloperoxidase CHEMBL2439 | IC50 | 5.52 | 5.52 | 3000.0 | 1 |
| Alternative oxidase, mitochondrial CHEMBL4295594 | IC50 | 5.23 | 5.23 | 5930.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 5.23 | 5.2067 | 5930.0 | 3 |
| Trypanosoma brucei brucei CHEMBL612851 | EC50 | 5.16 | 4.6986 | 7000.0 | 7 |
| Polyunsaturated fatty acid 5-lipoxygenase CHEMBL312 | IC50 | 4.52 | 4.52 | 30000.0 | 2 |
| Plasmodium falciparum CHEMBL364 | IC50 | 4.45 | 4.37 | 35481.3 | 4 |
Pharmacokinetic Data
| Parameter | Value | Units | Species |
|---|---|---|---|
| CL | 3.0 | mL.min-1.g-1 | Homo sapiens |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
Data from ChEMBL 36 via Core Engine