Compound Detail
CHEMBL1491847
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Basic Information
| ChEMBL ID | CHEMBL1491847 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GQKCBYFGTYNZCM-XGGBRTKESA-N |
8
Targets
26
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
465.8
MW (Da)
5.94
ALogP
3
HBA
3
HBD
36.1
PSA (Ų)
0.34
QED
1
Ro5 Violations
13
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 14 meas. best 6.29
IC50 12 meas. best 5.62
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| BJ CHEMBL614358 | EC50 | 6.29 | 5.715 | 509.0 | 4 |
| Unchecked CHEMBL612545 | IC50 | 5.62 | 4.892 | 2420.0 | 10 |
| Streptokinase A CHEMBL1293228 | EC50 | 5.53 | 5.53 | 2943.0 | 1 |
| Streptococcus sp. 'group A' CHEMBL612389 | EC50 | 5.49 | 5.49 | 3266.0 | 1 |
| Unchecked CHEMBL612545 | EC50 | 5.48 | 5.402 | 3280.0 | 5 |
| HEK293 CHEMBL614818 | IC50 | 5.47 | 5.47 | 3373.0 | 1 |
| Insulin-degrading enzyme CHEMBL1293287 | EC50 | 5.15 | 5.15 | 7021.0 | 1 |
| Streptococcus CHEMBL612313 | EC50 | 5.09 | 5.09 | 8100.0 | 1 |
| C-C chemokine receptor type 6 CHEMBL4423 | IC50 | 4.67 | 4.67 | 21400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine