Compound Detail
CHEMBL1994555
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Basic Information
| ChEMBL ID | CHEMBL1994555 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QZPFUALVXZAFDD-UHFFFAOYSA-N |
24
Targets
24
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
265.3
MW (Da)
3.39
ALogP
3
HBA
1
HBD
58.6
PSA (Ų)
0.74
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 24 meas. best 7.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Activin receptor type-1 CHEMBL5903 | Ki | 7.0 | 7.0 | 100.0 | 1 |
| Cyclin-dependent kinase 5 CHEMBL4036 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Cyclin-dependent kinase 8 CHEMBL5719 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Mitogen-activated protein kinase 8 CHEMBL2276 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Casein kinase I isoform alpha CHEMBL2793 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Aurora kinase A CHEMBL4722 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Cyclin-dependent kinase 9 CHEMBL3116 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Proto-oncogene tyrosine-protein kinase receptor Ret CHEMBL2041 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Leukocyte tyrosine kinase receptor CHEMBL5627 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Tyrosine-protein kinase ABL1 CHEMBL1862 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Serine/threonine-protein kinase TAO1 CHEMBL5261 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Leucine-rich repeat serine/threonine-protein kinase 2 CHEMBL1075104 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Serine/threonine-protein kinase PAK 4 CHEMBL4482 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| LIM domain kinase 1 CHEMBL3836 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Cyclin-dependent kinase 7 CHEMBL3055 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Tyrosine-protein kinase Fyn CHEMBL1841 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| ALK tyrosine kinase receptor CHEMBL4247 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Focal adhesion kinase 1 CHEMBL2695 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Data from ChEMBL 36 via Core Engine