| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 7.5 | 7.5 | 31.6 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B CHEMBL5543 | Ki | 7.0 | 7.0 | 100.0 | 1 |
| Cyclin-dependent kinase 5 CHEMBL4036 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Rho-associated protein kinase 1 CHEMBL3231 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Dual specificity protein kinase CLK2 CHEMBL4225 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Leucine-rich repeat serine/threonine-protein kinase 2 CHEMBL1075104 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Death-associated protein kinase 3 CHEMBL2468 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha CHEMBL4101 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Casein kinase I isoform alpha CHEMBL2793 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Cyclin-dependent kinase 9 CHEMBL3116 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Cyclin-dependent kinase 8 CHEMBL5719 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 1 CHEMBL3587 | Ki | 5.0 | 5.0 | 10000.0 | 1 |
| Mitogen-activated protein kinase 8 CHEMBL2276 | Ki | 4.9 | 4.9 | 12589.2 | 1 |
| Serine/threonine-protein kinase D3 CHEMBL2595 | Ki | 4.9 | 4.9 | 12589.2 | 1 |
| Protein kinase C theta type CHEMBL3920 | Ki | 4.9 | 4.9 | 12589.2 | 1 |
| Cyclin-dependent kinase 7 CHEMBL3055 | Ki | 4.9 | 4.9 | 12589.2 | 1 |
| cAMP-dependent protein kinase catalytic subunit PRKX CHEMBL5818 | Ki | 4.8 | 4.8 | 15848.9 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 2 CHEMBL2964 | Ki | 4.8 | 4.8 | 15848.9 | 1 |
| Aurora kinase A CHEMBL4722 | Ki | 4.8 | 4.8 | 15848.9 | 1 |
| Serine/threonine-protein kinase pim-1 CHEMBL2147 | Ki | 4.8 | 4.8 | 15848.9 | 1 |
| Activin receptor type-1 CHEMBL5903 | Ki | 4.7 | 4.7 | 19952.6 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 4.7 | 4.7 | 19952.6 | 1 |
| Leukocyte tyrosine kinase receptor CHEMBL5627 | Ki | 4.7 | 4.7 | 19952.6 | 1 |
| Fibroblast growth factor receptor 1 CHEMBL3650 | Ki | 4.7 | 4.7 | 19952.6 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit epsilon CHEMBL3529 | Ki | 4.7 | 4.7 | 19952.6 | 1 |
| Aurora kinase B CHEMBL2185 | Ki | 4.7 | 4.7 | 19952.6 | 1 |
| Calcium/calmodulin-dependent protein kinase type 1D CHEMBL5073 | Ki | 4.6 | 4.6 | 25118.9 | 1 |
| Vascular endothelial growth factor receptor 1 CHEMBL1868 | Ki | 4.6 | 4.6 | 25118.9 | 1 |
| Ribosomal protein S6 kinase alpha-3 CHEMBL2345 | Ki | 4.6 | 4.6 | 25118.9 | 1 |
| Tyrosine-protein kinase JAK2 CHEMBL2971 | Ki | 4.6 | 4.6 | 25118.9 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 CHEMBL4045 | Ki | 4.5 | 4.5 | 31622.8 | 1 |
| Hepatocyte growth factor receptor CHEMBL3717 | Ki | 4.5 | 4.5 | 31622.8 | 1 |
| Serine/threonine-protein kinase Nek2 CHEMBL3835 | Ki | 4.4 | 4.4 | 39810.7 | 1 |
| Macrophage-stimulating protein receptor CHEMBL2689 | Ki | 4.4 | 4.4 | 39810.7 | 1 |
| Platelet-derived growth factor receptor alpha CHEMBL2007 | Ki | 4.4 | 4.4 | 39810.7 | 1 |
| Serine/threonine-protein kinase Chk1 CHEMBL4630 | Ki | 4.4 | 4.4 | 39810.7 | 1 |
| G protein-coupled receptor kinase 5 CHEMBL5678 | Ki | 4.4 | 4.4 | 39810.7 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 2 CHEMBL5330 | Ki | 4.4 | 4.4 | 39810.7 | 1 |
| Platelet-derived growth factor receptor beta CHEMBL1913 | Ki | 4.3 | 4.3 | 50118.7 | 1 |
| Proto-oncogene tyrosine-protein kinase receptor Ret CHEMBL2041 | Ki | 4.3 | 4.3 | 50118.7 | 1 |
| Serine/threonine-protein kinase TBK1 CHEMBL5408 | Ki | 4.3 | 4.3 | 50118.7 | 1 |
| Focal adhesion kinase 1 CHEMBL2695 | Ki | 4.2 | 4.2 | 63095.7 | 1 |
| Tyrosine-protein kinase receptor TYRO3 CHEMBL5314 | Ki | 4.2 | 4.2 | 63095.7 | 1 |
| Serine/threonine-protein kinase TAO1 CHEMBL5261 | Ki | 4.1 | 4.1 | 79432.8 | 1 |
| ALK tyrosine kinase receptor CHEMBL4247 | Ki | 4.1 | 4.1 | 79432.8 | 1 |
| Mitogen-activated protein kinase 9 CHEMBL4179 | Ki | 4.1 | 4.1 | 79432.8 | 1 |