| Activin receptor type-1 CHEMBL5903 | Ki | 7.4 | 7.4 | 39.8 | 1 |
| Serine/threonine-protein kinase PLK4 CHEMBL3788 | Ki | 7.3 | 7.3 | 50.1 | 1 |
| Interleukin-1 receptor-associated kinase 1 CHEMBL3357 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| 3-phosphoinositide-dependent protein kinase 1 CHEMBL2534 | Ki | 6.9 | 6.9 | 125.9 | 1 |
| Tyrosine-protein kinase ITK/TSK CHEMBL2959 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Cell division cycle 7-related protein kinase CHEMBL5443 | Ki | 6.7 | 6.7 | 199.5 | 1 |
| Cyclin-dependent kinase 2 CHEMBL301 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Tyrosine-protein kinase FRK CHEMBL4223 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Proto-oncogene tyrosine-protein kinase Src CHEMBL267 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| Protein-tyrosine kinase 6 CHEMBL4601 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Activated CDC42 kinase 1 CHEMBL4599 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 2 CHEMBL5330 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Proto-oncogene tyrosine-protein kinase receptor Ret CHEMBL2041 | Ki | 6.5 | 6.5 | 316.2 | 1 |
| Serine/threonine-protein kinase Chk2 CHEMBL2527 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 6.4 | 6.4 | 398.1 | 1 |
| Tyrosine-protein kinase Blk CHEMBL2250 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Misshapen-like kinase 1 CHEMBL5518 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Tyrosine-protein kinase JAK2 CHEMBL2971 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| MAP/microtubule affinity-regulating kinase 3 CHEMBL5600 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Leucine-rich repeat serine/threonine-protein kinase 2 CHEMBL1075104 | Ki | 6.2 | 6.2 | 631.0 | 1 |
| Aurora kinase A CHEMBL4722 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Fibroblast growth factor receptor 3 CHEMBL2742 | Ki | 6.1 | 6.1 | 794.3 | 1 |
| Non-receptor tyrosine-protein kinase TYK2 CHEMBL3553 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Serine/threonine-protein kinase 17A CHEMBL4525 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| ALK tyrosine kinase receptor CHEMBL4247 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Tyrosine-protein kinase ABL1 CHEMBL1862 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform CHEMBL2349 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Tyrosine-protein kinase Lck CHEMBL258 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Tyrosine-protein kinase Fyn CHEMBL1841 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Macrophage colony-stimulating factor 1 receptor CHEMBL1844 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Cyclin-dependent kinase 8 CHEMBL5719 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Focal adhesion kinase 1 CHEMBL2695 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Serine/threonine-protein kinase PAK 4 CHEMBL4482 | Ki | 5.8 | 5.8 | 1584.9 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Mitogen-activated protein kinase 8 CHEMBL2276 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| STE20-like serine/threonine-protein kinase CHEMBL4202 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Mitogen-activated protein kinase kinase kinase 20 CHEMBL3886 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Cyclin-dependent kinase 1 CHEMBL308 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Ephrin type-A receptor 2 CHEMBL2068 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Fibroblast growth factor receptor 1 CHEMBL3650 | Ki | 5.6 | 5.6 | 2511.9 | 1 |
| Serine/threonine-protein kinase 3 CHEMBL4708 | Ki | 5.5 | 5.5 | 3162.3 | 1 |
| Serine/threonine-protein kinase Chk1 CHEMBL4630 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Mitogen-activated protein kinase 12 CHEMBL4674 | Ki | 5.4 | 5.4 | 3981.1 | 1 |
| Interleukin-1 receptor-associated kinase 4 CHEMBL3778 | Ki | 5.3 | 5.3 | 5011.9 | 1 |
| Casein kinase I isoform delta CHEMBL2828 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma CHEMBL3829 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Serine/threonine-protein kinase BRSK1 CHEMBL5650 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| RAC-alpha serine/threonine-protein kinase CHEMBL4282 | Ki | 5.1 | 5.1 | 7943.3 | 1 |