| Dual specificity protein kinase CLK4 CHEMBL4203 | Ki | 7.4 | 7.4 | 39.8 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha CHEMBL4101 | Ki | 7.1 | 7.1 | 79.4 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 1 CHEMBL3587 | Ki | 6.6 | 6.6 | 251.2 | 1 |
| cAMP-dependent protein kinase catalytic subunit PRKX CHEMBL5818 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Rho-associated protein kinase 1 CHEMBL3231 | Ki | 6.3 | 6.3 | 501.2 | 1 |
| Activin receptor type-1 CHEMBL5903 | Ki | 6.0 | 6.0 | 1000.0 | 1 |
| Leucine-rich repeat serine/threonine-protein kinase 2 CHEMBL1075104 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 2 CHEMBL2964 | Ki | 5.9 | 5.9 | 1258.9 | 1 |
| Dual specificity protein kinase CLK2 CHEMBL4225 | Ki | 5.7 | 5.7 | 1995.3 | 1 |
| Platelet-derived growth factor receptor beta CHEMBL1913 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B CHEMBL5543 | Ki | 5.2 | 5.2 | 6309.6 | 1 |
| Macrophage colony-stimulating factor 1 receptor CHEMBL1844 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| Casein kinase I isoform alpha CHEMBL2793 | Ki | 5.1 | 5.1 | 7943.3 | 1 |
| Tyrosine-protein kinase Lck CHEMBL258 | Ki | 5.0 | 5.0 | 10000.0 | 1 |
| Vascular endothelial growth factor receptor 2 CHEMBL279 | Ki | 4.9 | 4.9 | 12589.2 | 1 |
| Tyrosine-protein kinase ABL1 CHEMBL1862 | Ki | 4.8 | 4.8 | 15848.9 | 1 |
| Activated CDC42 kinase 1 CHEMBL4599 | Ki | 4.8 | 4.8 | 15848.9 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | Ki | 4.7 | 4.7 | 19952.6 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 CHEMBL6166 | Ki | 4.7 | 4.7 | 19952.6 | 1 |
| Proto-oncogene tyrosine-protein kinase receptor Ret CHEMBL2041 | Ki | 4.7 | 4.7 | 19952.6 | 1 |
| Cyclin-dependent kinase 5 CHEMBL4036 | Ki | 4.7 | 4.7 | 19952.6 | 1 |
| Protein kinase C theta type CHEMBL3920 | Ki | 4.7 | 4.7 | 19952.6 | 1 |
| Ribosomal protein S6 kinase alpha-3 CHEMBL2345 | Ki | 4.7 | 4.7 | 19952.6 | 1 |
| Cyclin-dependent kinase 7 CHEMBL3055 | Ki | 4.7 | 4.7 | 19952.6 | 1 |
| Glycogen synthase kinase-3 alpha CHEMBL2850 | Ki | 4.7 | 4.7 | 19952.6 | 1 |
| Focal adhesion kinase 1 CHEMBL2695 | Ki | 4.7 | 4.7 | 19952.6 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | Ki | 4.6 | 4.6 | 25118.9 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha CHEMBL4147 | Ki | 4.6 | 4.6 | 25118.9 | 1 |
| Hepatocyte growth factor receptor CHEMBL3717 | Ki | 4.5 | 4.5 | 31622.8 | 1 |
| G protein-coupled receptor kinase 5 CHEMBL5678 | Ki | 4.5 | 4.5 | 31622.8 | 1 |
| Leukocyte tyrosine kinase receptor CHEMBL5627 | Ki | 4.5 | 4.5 | 31622.8 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 2 CHEMBL5330 | Ki | 4.5 | 4.5 | 31622.8 | 1 |
| Death-associated protein kinase 3 CHEMBL2468 | Ki | 4.4 | 4.4 | 39810.7 | 1 |
| Tyrosine-protein kinase receptor TYRO3 CHEMBL5314 | Ki | 4.4 | 4.4 | 39810.7 | 1 |
| Mitogen-activated protein kinase 14 CHEMBL260 | Ki | 4.3 | 4.3 | 50118.7 | 1 |
| Insulin-like growth factor 1 receptor CHEMBL1957 | Ki | 4.3 | 4.3 | 50118.7 | 1 |
| Calcium/calmodulin-dependent protein kinase type 1D CHEMBL5073 | Ki | 4.3 | 4.3 | 50118.7 | 1 |
| Serine/threonine-protein kinase PAK 4 CHEMBL4482 | Ki | 4.3 | 4.3 | 50118.7 | 1 |
| Mitogen-activated protein kinase 8 CHEMBL2276 | Ki | 4.3 | 4.3 | 50118.7 | 1 |
| Mitogen-activated protein kinase 9 CHEMBL4179 | Ki | 4.3 | 4.3 | 50118.7 | 1 |
| High affinity nerve growth factor receptor CHEMBL2815 | Ki | 4.3 | 4.3 | 50118.7 | 1 |
| ALK tyrosine kinase receptor CHEMBL4247 | Ki | 4.2 | 4.2 | 63095.7 | 1 |
| Macrophage-stimulating protein receptor CHEMBL2689 | Ki | 4.2 | 4.2 | 63095.7 | 1 |
| Fibroblast growth factor receptor 1 CHEMBL3650 | Ki | 4.2 | 4.2 | 63095.7 | 1 |
| Serine/threonine-protein kinase D3 CHEMBL2595 | Ki | 4.1 | 4.1 | 79432.8 | 1 |
| Vascular endothelial growth factor receptor 1 CHEMBL1868 | Ki | 4.1 | 4.1 | 79432.8 | 1 |